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Antibiotic Susceptibility Patterns of Urinary Pathogens in Female Outpatients

BACKGROUND: Urinary tract Infection (UTI) is among the most common infections described in outpatient setting and hospital patients. In almost all cases empirical antimicrobial treatment initiates before the laboratory results of urine culture are available; thus antibiotic resistance may increase i...

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Autores principales: Shaifali, Iram, Gupta, Uma, Mahmood, Syed Esam, Ahmed, Jawed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334255/
https://www.ncbi.nlm.nih.gov/pubmed/22536558
http://dx.doi.org/10.4103/1947-2714.94940
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author Shaifali, Iram
Gupta, Uma
Mahmood, Syed Esam
Ahmed, Jawed
author_facet Shaifali, Iram
Gupta, Uma
Mahmood, Syed Esam
Ahmed, Jawed
author_sort Shaifali, Iram
collection PubMed
description BACKGROUND: Urinary tract Infection (UTI) is among the most common infections described in outpatient setting and hospital patients. In almost all cases empirical antimicrobial treatment initiates before the laboratory results of urine culture are available; thus antibiotic resistance may increase in uropathogens due to frequent use of antibiotics. AIMS: The study was designed to find the prevalence of UTI in females with urinary tract symptoms, to determine the causative organism (s) of UTI, and to determine the antibiotic susceptibility pattern of microbial agents isolated from urine culture (antibiogram). MATERIALS AND METHODS: The prospective, observational study involved 139 females, aged 15 years and above clinically suspected for UTI attending outpatient Departments of Vivekananda Polyclinic and Institute of Medical Sciences, Lucknow. A structured questionnaire was used to interview the study subjects. A chi-square test and Fisher Exact test were used to analyze data. RESULTS: The overall prevalence of UTI was found to be 45.32% (63/139). Escherichia coli (33.1%) and Klebsiella pneumoniae (7.9%) were the most common organisms isolated. The most effective antibiotic for both was Nitrofurantoin. CONCLUSIONS: Regular monitoring is required to establish reliable information about susceptibility pattern of urinary pathogens for optimal empirical therapy of patients with UTI.
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spelling pubmed-33342552012-04-25 Antibiotic Susceptibility Patterns of Urinary Pathogens in Female Outpatients Shaifali, Iram Gupta, Uma Mahmood, Syed Esam Ahmed, Jawed N Am J Med Sci Original Article BACKGROUND: Urinary tract Infection (UTI) is among the most common infections described in outpatient setting and hospital patients. In almost all cases empirical antimicrobial treatment initiates before the laboratory results of urine culture are available; thus antibiotic resistance may increase in uropathogens due to frequent use of antibiotics. AIMS: The study was designed to find the prevalence of UTI in females with urinary tract symptoms, to determine the causative organism (s) of UTI, and to determine the antibiotic susceptibility pattern of microbial agents isolated from urine culture (antibiogram). MATERIALS AND METHODS: The prospective, observational study involved 139 females, aged 15 years and above clinically suspected for UTI attending outpatient Departments of Vivekananda Polyclinic and Institute of Medical Sciences, Lucknow. A structured questionnaire was used to interview the study subjects. A chi-square test and Fisher Exact test were used to analyze data. RESULTS: The overall prevalence of UTI was found to be 45.32% (63/139). Escherichia coli (33.1%) and Klebsiella pneumoniae (7.9%) were the most common organisms isolated. The most effective antibiotic for both was Nitrofurantoin. CONCLUSIONS: Regular monitoring is required to establish reliable information about susceptibility pattern of urinary pathogens for optimal empirical therapy of patients with UTI. Medknow Publications & Media Pvt Ltd 2012-04 /pmc/articles/PMC3334255/ /pubmed/22536558 http://dx.doi.org/10.4103/1947-2714.94940 Text en Copyright: © North American Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Shaifali, Iram
Gupta, Uma
Mahmood, Syed Esam
Ahmed, Jawed
Antibiotic Susceptibility Patterns of Urinary Pathogens in Female Outpatients
title Antibiotic Susceptibility Patterns of Urinary Pathogens in Female Outpatients
title_full Antibiotic Susceptibility Patterns of Urinary Pathogens in Female Outpatients
title_fullStr Antibiotic Susceptibility Patterns of Urinary Pathogens in Female Outpatients
title_full_unstemmed Antibiotic Susceptibility Patterns of Urinary Pathogens in Female Outpatients
title_short Antibiotic Susceptibility Patterns of Urinary Pathogens in Female Outpatients
title_sort antibiotic susceptibility patterns of urinary pathogens in female outpatients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334255/
https://www.ncbi.nlm.nih.gov/pubmed/22536558
http://dx.doi.org/10.4103/1947-2714.94940
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