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Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success

The hypoxia inducible transcription factors (HIFs) control many mediators of vascular response, including both angiogenic factors and small molecules such as nitric oxide (NO). In studying how endothelial HIF response itself affects metastasis, we found that loss of HIF-1α in endothelial cells reduc...

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Detalles Bibliográficos
Autores principales: Branco-Price, Cristina, Zhang, Na, Schnelle, Moritz, Evans, Colin, Katschinski, Dörthe M., Liao, Debbie, Ellies, Lesley, Johnson, Randall S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334270/
https://www.ncbi.nlm.nih.gov/pubmed/22264788
http://dx.doi.org/10.1016/j.ccr.2011.11.017

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