Loss of protein expression and recurrent DNA hypermethylation of the GNG7 gene in squamous cell carcinoma of the head and neck

Although down-regulation of GNG7 in cancer was reported before, its role in carcinogenesis is poorly understood. It belongs to a family of large G-proteins that may be involved in cell-contact-induced growth arrest and function in tumor suppression. In the present study, we stained immunohistochemic...

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Detalles Bibliográficos
Autores principales: Hartmann, Sylvia, Szaumkessel, Marcin, Salaverria, Itziar, Simon, Ronald, Sauter, Guido, Kiwerska, Katarzyna, Gawecki, Wojciech, Bodnar, Magdalena, Marszalek, Andrzej, Richter, Julia, Brauze, Damian, Zemke, Natalia, Jarmuz, Malgorzata, Hansmann, Martin-Leo, Siebert, Reiner, Szyfter, Krzysztof, Giefing, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Human Genetics • Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334494/
https://www.ncbi.nlm.nih.gov/pubmed/22183866
http://dx.doi.org/10.1007/s13353-011-0079-4

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