The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls

BACKGROUND: The R620W variant in protein tyrosine phosphatase non-receptor 22 (PTPN22) is associated with rheumatoid arthritis (RA). The PTPN22 gene has alternatively spliced transcripts and at least two of the splice forms have been confirmed to encode different PTPN22 (LYP) proteins, but detailed...

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Detalles Bibliográficos
Autores principales: Ronninger, Marcus, Guo, Yongjing, Shchetynsky, Klementy, Hill, Andrew, Khademi, Mohsen, Olsson, Tomas, Reddy, Padmalatha S, Seddighzadeh, Maria, Clark, James D, Lin, Lih-Ling, O'Toole, Margot, Padyukov, Leonid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334550/
https://www.ncbi.nlm.nih.gov/pubmed/22264340
http://dx.doi.org/10.1186/gm301

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