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Recycling side-effects into clinical markers for drug repositioning
Side-effects are the unintended consequence of therapeutic treatments, but they can also be seen as valuable read-outs of drug effects in humans; these effects are difficult to infer or predict from pre-clinical models. Indeed, some studies suggest that drugs with similar side-effect profiles may al...
Autores principales: | Duran-Frigola, Miquel, Aloy, Patrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334551/ https://www.ncbi.nlm.nih.gov/pubmed/22283977 http://dx.doi.org/10.1186/gm302 |
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