Transcriptional enhancers in development and disease

Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease.

Detalles Bibliográficos
Autores principales: Sakabe, Noboru Jo, Savic, Daniel, Nobrega, Marcelo A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334578/
https://www.ncbi.nlm.nih.gov/pubmed/22269347
http://dx.doi.org/10.1186/gb-2012-13-1-238
Descripción
Sumario:Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease.

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