Transcriptional enhancers in development and disease

Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease.

Detalles Bibliográficos
Autores principales: Sakabe, Noboru Jo, Savic, Daniel, Nobrega, Marcelo A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334578/
https://www.ncbi.nlm.nih.gov/pubmed/22269347
http://dx.doi.org/10.1186/gb-2012-13-1-238
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author Sakabe, Noboru Jo
Savic, Daniel
Nobrega, Marcelo A
author_facet Sakabe, Noboru Jo
Savic, Daniel
Nobrega, Marcelo A
author_sort Sakabe, Noboru Jo
collection PubMed
description Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease.
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spelling pubmed-33345782013-01-23 Transcriptional enhancers in development and disease Sakabe, Noboru Jo Savic, Daniel Nobrega, Marcelo A Genome Biol Review Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can lead to disease. BioMed Central 2012 2012-01-23 /pmc/articles/PMC3334578/ /pubmed/22269347 http://dx.doi.org/10.1186/gb-2012-13-1-238 Text en Copyright ©2012 BioMed Central Ltd.
spellingShingle Review
Sakabe, Noboru Jo
Savic, Daniel
Nobrega, Marcelo A
Transcriptional enhancers in development and disease
title Transcriptional enhancers in development and disease
title_full Transcriptional enhancers in development and disease
title_fullStr Transcriptional enhancers in development and disease
title_full_unstemmed Transcriptional enhancers in development and disease
title_short Transcriptional enhancers in development and disease
title_sort transcriptional enhancers in development and disease
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334578/
https://www.ncbi.nlm.nih.gov/pubmed/22269347
http://dx.doi.org/10.1186/gb-2012-13-1-238
work_keys_str_mv AT sakabenoborujo transcriptionalenhancersindevelopmentanddisease
AT savicdaniel transcriptionalenhancersindevelopmentanddisease
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