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Implications for health and disease in the genetic signature of the Ashkenazi Jewish population

BACKGROUND: Relatively small, reproductively isolated populations with reduced genetic diversity may have advantages for genomewide association mapping in disease genetics. The Ashkenazi Jewish population represents a unique population for study based on its recent (< 1,000 year) history of a lim...

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Detalles Bibliográficos
Autores principales: Guha, Saurav, Rosenfeld, Jeffrey A, Malhotra, Anil K, Lee, Annette T, Gregersen, Peter K, Kane, John M, Pe'er, Itsik, Darvasi, Ariel, Lencz, Todd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334583/
https://www.ncbi.nlm.nih.gov/pubmed/22277159
http://dx.doi.org/10.1186/gb-2012-13-1-r2