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SpliceGrapher: detecting patterns of alternative splicing from RNA-Seq data in the context of gene models and EST data
We propose a method for predicting splice graphs that enhances curated gene models using evidence from RNA-Seq and EST alignments. Results obtained using RNA-Seq experiments in Arabidopsis thaliana show that predictions made by our SpliceGrapher method are more consistent with current gene models th...
Autores principales: | Rogers, Mark F, Thomas, Julie, Reddy, Anireddy SN, Ben-Hur, Asa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334585/ https://www.ncbi.nlm.nih.gov/pubmed/22293517 http://dx.doi.org/10.1186/gb-2012-13-1-r4 |
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