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Making enhancers from spare parts of the genome

New studies show that novel long-range enhancers of developmental genes can emerge by exaptation of protein-coding sequences with no previous regulatory function.

Detalles Bibliográficos
Autores principales: Fredman, David, Dong, Xianjun, Lenhard, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334608/
https://www.ncbi.nlm.nih.gov/pubmed/22206586
http://dx.doi.org/10.1186/gb-2011-12-12-138
Descripción
Sumario:New studies show that novel long-range enhancers of developmental genes can emerge by exaptation of protein-coding sequences with no previous regulatory function.