Cargando…

Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome

INTRODUCTION: In Sjögren's syndrome, keratoconjunctivitis sicca (dry eye) is associated with infiltration of lacrimal glands by leukocytes and consequent losses of tear-fluid production and the integrity of the ocular surface. We investigated the effect of blockade of the lymphotoxin-beta recep...

Descripción completa

Detalles Bibliográficos
Autores principales: Fava, Roy A, Kennedy, Susan M, Wood, Sheryl G, Bolstad, Anne I, Bienkowska, Jadwiga, Papandile, Adrian, Kelly, John A, Mavragani, Clio P, Gatumu, Margaret, Skarstein, Kathrine, Browning, Jeffrey L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334628/
https://www.ncbi.nlm.nih.gov/pubmed/22044682
http://dx.doi.org/10.1186/ar3507