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Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome
INTRODUCTION: In Sjögren's syndrome, keratoconjunctivitis sicca (dry eye) is associated with infiltration of lacrimal glands by leukocytes and consequent losses of tear-fluid production and the integrity of the ocular surface. We investigated the effect of blockade of the lymphotoxin-beta recep...
Autores principales: | Fava, Roy A, Kennedy, Susan M, Wood, Sheryl G, Bolstad, Anne I, Bienkowska, Jadwiga, Papandile, Adrian, Kelly, John A, Mavragani, Clio P, Gatumu, Margaret, Skarstein, Kathrine, Browning, Jeffrey L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334628/ https://www.ncbi.nlm.nih.gov/pubmed/22044682 http://dx.doi.org/10.1186/ar3507 |
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