Cargando…

Lymphotoxin-beta receptor blockade reduces CXCL13 in lacrimal glands and improves corneal integrity in the NOD model of Sjögren's syndrome

INTRODUCTION: In Sjögren's syndrome, keratoconjunctivitis sicca (dry eye) is associated with infiltration of lacrimal glands by leukocytes and consequent losses of tear-fluid production and the integrity of the ocular surface. We investigated the effect of blockade of the lymphotoxin-beta recep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fava, Roy A, Kennedy, Susan M, Wood, Sheryl G, Bolstad, Anne I, Bienkowska, Jadwiga, Papandile, Adrian, Kelly, John A, Mavragani, Clio P, Gatumu, Margaret, Skarstein, Kathrine, Browning, Jeffrey L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334628/ https://www.ncbi.nlm.nih.gov/pubmed/22044682 http://dx.doi.org/10.1186/ar3507

Ejemplares similares

Blockade of lymphotoxin-beta receptor signaling reduces aspects of Sjögren's syndrome in salivary glands of non-obese diabetic mice
por: Gatumu, Margaret K, et al.
Publicado: (2009)

Epidemiology of Sjögren’s Syndrome—from an Oral Perspective
por: Bolstad, Anne Isine, et al.
Publicado: (2016)

Contribution of Genetic Factors to Sjögren's Syndrome and Sjögren's Syndrome Related Lymphomagenesis
por: Nezos, Adrianos, et al.
Publicado: (2015)

Lymphotoxin-LIGHT Pathway Regulates the Interferon Signature in Rheumatoid Arthritis
por: Bienkowska, Jadwiga, et al.
Publicado: (2014)

Editorial: Management of Sjögren's Syndrome
por: Alunno, Alessia, et al.
Publicado: (2022)

Sjogren’s Syndrome: Recent Updates
por: Skarlis, Charalampos, et al.
Publicado: (2022)

Arginase 1 is involved in lacrimal hyposecretion in male NOD mice, a model of Sjögren's syndrome, regardless of dacryoadenitis status
por: Ohno, Yuta, et al.
Publicado: (2020)

Predicting the risk for lymphoma development in Sjogren syndrome: An easy tool for clinical use
por: Fragkioudaki, Sofia, et al.
Publicado: (2016)

Musculoskeletal Manifestations in Sjogren’s Syndrome: An Orthopedic Point of View
por: Rozis, Meletios, et al.
Publicado: (2021)

Bilateral Lacrimal Gland Lymphoma in Sjögren Syndrome
por: Palamar, Melis, et al.
Publicado: (2016)

Current concepts on Sjögren's syndrome – classification criteria and biomarkers
por: Jonsson, Roland, et al.
Publicado: (2018)

Milk Fat Globule Epidermal Growth Factor 8 (MFGE8) Gene Variants in Rheumatoid Arthritis and Sjögren’s Syndrome
por: Skarlis, Charalampos, et al.
Publicado: (2022)

Vitamin D Deficiency in Primary Sjögren’s Syndrome: Association with Clinical Manifestations and Immune Activation Markers
por: Athanassiou, Panagiotis, et al.
Publicado: (2022)

Sjögren-Like Lacrimal Keratoconjunctivitis in Germ-Free Mice
por: Wang, Changjun, et al.
Publicado: (2018)

Study of the incidence of osteoporosis in patients with Sjögren’s syndrome (pSS) and investigation of activation of the RANKL /RANK and osteoprotegerin (OPG) system
por: Skarlis, Charalampos, et al.
Publicado: (2018)

A case with acquired lacrimal fistula due to Sjögren's syndrome
por: Ishikawa, Sho, et al.
Publicado: (2019)

TNFAIP3 F127C Coding Variation in Greek Primary Sjogren's Syndrome Patients
por: Nezos, Adrianos, et al.
Publicado: (2018)

Interferon-γ treatment in vitro elicits some of the changes in cathepsin S and antigen presentation characteristic of lacrimal glands and corneas from the NOD mouse model of Sjögren’s Syndrome
por: Meng, Zhen, et al.
Publicado: (2017)

Predicting the Outcome of Sjogren’s Syndrome-Associated Non-Hodgkin’s Lymphoma Patients
por: Papageorgiou, Aristea, et al.
Publicado: (2015)

TLR7 Signaling Drives the Development of Sjögren’s Syndrome
por: Wang, Yawen, et al.
Publicado: (2021)

Aire-deficient mice provide a model of corneal and lacrimal gland neuropathy in Sjögren's syndrome
por: Chen, Feeling Y., et al.
Publicado: (2017)

The Sequential Role of Lymphotoxin and B Cells in the Development of Splenic Follicles
por: Gonzalez, Mercedes, et al.
Publicado: (1998)

The Requirement of Membrane Lymphotoxin for the Presence of Dendritic Cells in Lymphoid Tissues
por: Wu, Qiang, et al.
Publicado: (1999)

Salivary glands of primary Sjögren's syndrome patients express factors vital for plasma cell survival
por: Szyszko, Ewa A, et al.
Publicado: (2011)

Molecular Evidence for Precursors of Sjögren’s Foci in Histologically Normal Lacrimal Glands
por: Mircheff, Austin K., et al.
Publicado: (2019)

Role of the Lymphotoxin/LIGHT System in the Development and Maintenance of Reticular Networks and Vasculature in Lymphoid Tissues
por: Lu, Theresa T., et al.
Publicado: (2014)

Scleroderma specific autoantibodies in rheumatoid arthritis and Sjögren's syndrome patients with interstitial lung disease: Prevalence and associations
por: Koulouri, Vasiliki, et al.
Publicado: (2022)

Sex Effects on Gene Expression in Lacrimal Glands of Mouse Models of Sjögren Syndrome
por: Tellefsen, Sara, et al.
Publicado: (2018)

Testosterone Influence on Gene Expression in Lacrimal Glands of Mouse Models of Sjögren Syndrome
por: Morthen, Mathias Kaurstad, et al.
Publicado: (2019)

Potential therapeutic approach for the hormonal treatment of lacrimal gland dysfunction in Sjögren's syndrome
por: Sullivan, David A., et al.
Publicado: (1992)

The use of Schirmer strips to measure salivary and lacrimal flow in non-Sjögren patients
por: Wróbel-Dudzińska, Dominika, et al.
Publicado: (2021)

Genetic aspects of Sjögren's syndrome
por: Bolstad, Anne Isine, et al.
Publicado: (2002)

Genomic organization and phylogenetic utility of deer mouse (Peromyscus maniculatus) lymphotoxin-alpha and lymphotoxin-beta
por: Richens, Tiffany, et al.
Publicado: (2008)

Inflammatory Stratification in Primary Sjögren’s Syndrome Reveals Novel Immune Cell Alterations in Patients’ Minor Salivary Glands
por: Bharaj, Tamandeep K., et al.
Publicado: (2021)

Subclinical atherosclerosis and impaired bone health in patients with primary Sjogren’s syndrome: prevalence, clinical and laboratory associations
por: Gravani, Fotini, et al.
Publicado: (2015)

Temporal histological changes in lacrimal and major salivary glands in mouse models of Sjogren’s syndrome
por: Xuan, Jingxiu, et al.
Publicado: (2013)

The Diagnostic Value of MRI-Based Radiomic Analysis of Lacrimal Glands in Patients with Sjögren’s Syndrome
por: Muntean, Delia Doris, et al.
Publicado: (2022)

Inhibition of lysophosphatidic acid receptor ameliorates Sjögren's syndrome in NOD mice
por: Park, Eunhye, et al.
Publicado: (2017)

Genetic Variants of the BAFF Gene and Risk of Fatigue Among Patients With Primary Sjögren’s Syndrome
por: Flessa, Christina-Maria, et al.
Publicado: (2022)

Lymphotoxin-sensitive microenvironments in homeostasis and inflammation
por: Boulianne, Bryant, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_rn6u8s2469subm4gcc0dlr5v0l