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Decreased CXCR1 and CXCR2 expression on neutrophils in anti-neutrophil cytoplasmic autoantibody-associated vasculitides potentially increases neutrophil adhesion and impairs migration
INTRODUCTION: In anti-neutrophil cytoplasmic autoantibody (ANCA)-associated vasculitides (AAV), persistent inflammation within the vessel wall suggests perturbed neutrophil trafficking leading to accumulation of activated neutrophils in the microvascular compartment. CXCR1 and CXCR2, being major che...
Autores principales: | Hu, Nan, Westra, Johanna, Rutgers, Abraham, Doornbos-Van der Meer, Berber, Huitema, Minke G, Stegeman, Coen A, Abdulahad, Wayel H, Satchell, Simon C, Mathieson, Peter W, Heeringa, Peter, M Kallenberg, Cees G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334654/ https://www.ncbi.nlm.nih.gov/pubmed/22152684 http://dx.doi.org/10.1186/ar3534 |
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