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Mutations in genes encoding complement inhibitors CD46 and CFH affect the age at nephritis onset in patients with systemic lupus erythematosus

INTRODUCTION: Inherited deficiencies of several complement components strongly predispose to systemic lupus erythematosus (SLE) while deficiencies of complement inhibitors are found in kidney diseases such as atypical hemolytic uremic syndrome (aHUS). METHODS: The exons of complement inhibitor genes...

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Detalles Bibliográficos
Autores principales:	Jönsen, Andreas, Nilsson, Sara C, Ahlqvist, Emma, Svenungsson, Elisabet, Gunnarsson, Iva, Eriksson, Karin G, Bengtsson, Anders, Zickert, Agneta, Eloranta, Maija-Leena, Truedsson, Lennart, Rönnblom, Lars, Nordmark, Gunnel, Sturfelt, Gunnar, Blom, Anna M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334659/ https://www.ncbi.nlm.nih.gov/pubmed/22171659 http://dx.doi.org/10.1186/ar3539

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