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Application of in vivo micro-computed tomography in the temporal characterisation of subchondral bone architecture in a rat model of low-dose monosodium iodoacetate-induced osteoarthritis
INTRODUCTION: Osteoarthritis (OA) is a complex, multifactorial joint disease affecting both the cartilage and the subchondral bone. Animal models of OA aid in the understanding of the pathogenesis of OA and testing suitable drugs for OA treatment. In this study we characterized the temporal changes...
Autores principales: | Mohan, Geetha, Perilli, Egon, Kuliwaba, Julia S, Humphries, Julia M, Parkinson, Ian H, Fazzalari, Nicola L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334663/ https://www.ncbi.nlm.nih.gov/pubmed/22185204 http://dx.doi.org/10.1186/ar3543 |
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