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Leukotrienes inhibit early stages of HIV-1 infection in monocyte-derived microglia-like cells

BACKGROUND: Microglia are one of the main cell types to be productively infected by HIV-1 in the central nervous system (CNS). Leukotriene B(4 )(LTB(4)) and cysteinyl-leukotrienes such as LTC(4 )are some of the proinflammatory molecules produced in infected individuals that contribute to neuroinflam...

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Detalles Bibliográficos
Autores principales: Bertin, Jonathan, Barat, Corinne, Bélanger, Dave, Tremblay, Michel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334677/
https://www.ncbi.nlm.nih.gov/pubmed/22424294
http://dx.doi.org/10.1186/1742-2094-9-55