Coenzyme Q(10 )deficiency in septic shock patients

Donnino and colleagues provide new insights into the field of oxidative stress and mitochondrial dysfunction during septic shock. These authors suggest a coenzyme Q(10 )(CoQ(10)) deficiency in patients with septic shock. Larger prospective observational trials measuring CoQ(10 )in patients with sept...

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Detalles Bibliográficos
Autores principales: Dupic, Laurent, Huet, Olivier, Duranteau, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334745/
https://www.ncbi.nlm.nih.gov/pubmed/22011617
http://dx.doi.org/10.1186/cc10429
Descripción
Sumario:Donnino and colleagues provide new insights into the field of oxidative stress and mitochondrial dysfunction during septic shock. These authors suggest a coenzyme Q(10 )(CoQ(10)) deficiency in patients with septic shock. Larger prospective observational trials measuring CoQ(10 )in patients with septic shock are required to confirm the possibility of CoQ(10 )depletion. This study is a new step toward a study testing CoQ(10 )as a potential therapeutic agent for patients with septic shock.

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