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Pharmacokinetics of prolonged infusion of high-dose dexmedetomidine in critically ill patients

INTRODUCTION: Only limited information exists on the pharmacokinetics of prolonged (> 24 hours) and high-dose dexmedetomidine infusions in critically ill patients. The aim of this study was to characterize the pharmacokinetics of long dexmedetomidine infusions and to assess the dose linearity of...

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Detalles Bibliográficos
Autores principales:	Iirola, Timo, Aantaa, Riku, Laitio, Ruut, Kentala, Erkki, Lahtinen, Maria, Wighton, Andrew, Garratt, Chris, Ahtola-Sätilä, Tuula, Olkkola, Klaus T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334808/ https://www.ncbi.nlm.nih.gov/pubmed/22030215 http://dx.doi.org/10.1186/cc10518

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