GlialCAM, a Protein Defective in a Leukodystrophy, Serves as a ClC-2 Cl(−) Channel Auxiliary Subunit

Ion fluxes mediated by glial cells are required for several physiological processes such as fluid homeostasis or the maintenance of low extracellular potassium during high neuronal activity. In mice, the disruption of the Cl(−) channel ClC-2 causes fluid accumulation leading to myelin vacuolation. A...

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Detalles Bibliográficos
Autores principales: Jeworutzki, Elena, López-Hernández, Tania, Capdevila-Nortes, Xavier, Sirisi, Sònia, Bengtsson, Luiza, Montolio, Marisol, Zifarelli, Giovanni, Arnedo, Tanit, Müller, Catrin S., Schulte, Uwe, Nunes, Virginia, Martínez, Albert, Jentsch, Thomas J., Gasull, Xavier, Pusch, Michael, Estévez, Raúl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334819/
https://www.ncbi.nlm.nih.gov/pubmed/22405205
http://dx.doi.org/10.1016/j.neuron.2011.12.039

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