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PIWI Associated siRNAs and piRNAs Specifically Require the Caenorhabditis elegans HEN1 Ortholog henn-1

Small RNAs—including piRNAs, miRNAs, and endogenous siRNAs—bind Argonaute proteins to form RNA silencing complexes that target coding genes, transposons, and aberrant RNAs. To assess the requirements for endogenous siRNA formation and activity in Caenorhabditis elegans, we developed a GFP-based sens...

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Detalles Bibliográficos
Autores principales:	Montgomery, Taiowa A., Rim, Young-Soo, Zhang, Chi, Dowen, Robert H., Phillips, Carolyn M., Fischer, Sylvia E. J., Ruvkun, Gary
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334881/ https://www.ncbi.nlm.nih.gov/pubmed/22536158 http://dx.doi.org/10.1371/journal.pgen.1002616

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