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How does viral DNA find the nucleus of an infected cell?

If all locations of a living cell would have the same chemical potential, most viral infections of a cell should be abortive, even after the a penetration of the cell wall by the viral DNA-polymer or viral RNA-polymer occurred. This is obviously not the case. Therefore, there must be a mechanism whi...

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Detalles Bibliográficos
Autor principal: Widulle, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: German Medical Science GMS Publishing House 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334944/
https://www.ncbi.nlm.nih.gov/pubmed/22558035
http://dx.doi.org/10.3205/dgkh000185
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author Widulle, Herbert
author_facet Widulle, Herbert
author_sort Widulle, Herbert
collection PubMed
description If all locations of a living cell would have the same chemical potential, most viral infections of a cell should be abortive, even after the a penetration of the cell wall by the viral DNA-polymer or viral RNA-polymer occurred. This is obviously not the case. Therefore, there must be a mechanism which transports a viral DNA-polymer from the cell wall to the nucleus and not to any other location. A possible mechanism is proposed which is in accordance with biophysical chemistry. The presented description of the mechanism uses non equilibrium thermodynamics to find a simple solution for the problem.
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spelling pubmed-33349442012-05-03 How does viral DNA find the nucleus of an infected cell? Widulle, Herbert GMS Krankenhhyg Interdiszip Article If all locations of a living cell would have the same chemical potential, most viral infections of a cell should be abortive, even after the a penetration of the cell wall by the viral DNA-polymer or viral RNA-polymer occurred. This is obviously not the case. Therefore, there must be a mechanism which transports a viral DNA-polymer from the cell wall to the nucleus and not to any other location. A possible mechanism is proposed which is in accordance with biophysical chemistry. The presented description of the mechanism uses non equilibrium thermodynamics to find a simple solution for the problem. German Medical Science GMS Publishing House 2012-04-04 /pmc/articles/PMC3334944/ /pubmed/22558035 http://dx.doi.org/10.3205/dgkh000185 Text en Copyright © 2012 Widulle http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc-nd/3.0/deed.en). You are free to copy, distribute and transmit the work, provided the original author and source are credited.
spellingShingle Article
Widulle, Herbert
How does viral DNA find the nucleus of an infected cell?
title How does viral DNA find the nucleus of an infected cell?
title_full How does viral DNA find the nucleus of an infected cell?
title_fullStr How does viral DNA find the nucleus of an infected cell?
title_full_unstemmed How does viral DNA find the nucleus of an infected cell?
title_short How does viral DNA find the nucleus of an infected cell?
title_sort how does viral dna find the nucleus of an infected cell?
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334944/
https://www.ncbi.nlm.nih.gov/pubmed/22558035
http://dx.doi.org/10.3205/dgkh000185
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