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DW-MRI as a Biomarker to Compare Therapeutic Outcomes in Radiotherapy Regimens Incorporating Temozolomide or Gemcitabine in Glioblastoma

The effectiveness of the radiosensitizer gemcitabine (GEM) was evaluated in a mouse glioma along with the imaging biomarker diffusion-weighted magnetic resonance imaging (DW-MRI) for early detection of treatment effects. A genetically engineered murine GBM model [Ink4a-Arf(−/−) Pten(loxP/loxP)/Ntv-a...

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Detalles Bibliográficos
Autores principales: Galbán, Stefanie, Lemasson, Benjamin, Williams, Terence M., Li, Fei, Heist, Kevin A., Johnson, Timothy D., Leopold, Judith S., Chenevert, Thomas L., Lawrence, Theodore S., Rehemtulla, Alnawaz, Mikkelsen, Tom, Holland, Eric C., Galbán, Craig J., Ross, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334987/
https://www.ncbi.nlm.nih.gov/pubmed/22536446
http://dx.doi.org/10.1371/journal.pone.0035857