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Automatic Design of Synthetic Gene Circuits through Mixed Integer Non-linear Programming
Automatic design of synthetic gene circuits poses a significant challenge to synthetic biology, primarily due to the complexity of biological systems, and the lack of rigorous optimization methods that can cope with the combinatorial explosion as the number of biological parts increases. Current opt...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334995/ https://www.ncbi.nlm.nih.gov/pubmed/22536398 http://dx.doi.org/10.1371/journal.pone.0035529 |