Impact of the Location of CpG Methylation within the GSTP1 Gene on Its Specificity as a DNA Marker for Hepatocellular Carcinoma

Hypermethylation of the glutathione S-transferase π 1 (GSTP1) gene promoter region has been reported to be a potential biomarker to distinguish hepatocellular carcinoma (HCC) from other liver diseases. However, reports regarding how specific a marker it is have ranged from 100% to 0%. We hypothesize...

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Detalles Bibliográficos
Autores principales: Jain, Surbhi, Chen, Sitong, Chang, Kung-Chao, Lin, Yih-Jyh, Hu, Chi-Tan, Boldbaatar, Batbold, Hamilton, James P., Lin, Selena Y., Chang, Ting-Tsung, Chen, Shun-Hua, Song, Wei, Meltzer, Stephen J., Block, Timothy M., Su, Ying-Hsiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335004/
https://www.ncbi.nlm.nih.gov/pubmed/22536438
http://dx.doi.org/10.1371/journal.pone.0035789

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