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Glucose-Dependent Insulinotropic Polypeptide Prevents the Progression of Macrophage-Driven Atherosclerosis in Diabetic Apolipoprotein E-Null Mice

AIM: We recently reported that glucose-dependent insulinotropic polypeptide (GIP) prevents the development of atherosclerosis in apolipoprotein E-null (Apoe (−/−)) mice. GIP receptors (GIPRs) are found to be severely down-regulated in diabetic animals. We examined whether GIP can exert anti-atheroge...

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Detalles Bibliográficos
Autores principales: Nogi, Yukinori, Nagashima, Masaharu, Terasaki, Michishige, Nohtomi, Kyoko, Watanabe, Takuya, Hirano, Tsutomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335006/
https://www.ncbi.nlm.nih.gov/pubmed/22536426
http://dx.doi.org/10.1371/journal.pone.0035683