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ANG-1 TIE-2 and BMPR Signalling Defects Are Not Seen in the Nitrofen Model of Pulmonary Hypertension and Congenital Diaphragmatic Hernia
BACKGROUND: Pulmonary hypertension (PH) is a lethal disease that is associated with characteristic histological abnormalities of the lung vasculature and defects of angiopoetin-1 (ANG-1), TIE-2 and bone morphogenetic protein receptor (BMPR)-related signalling. We hypothesized that if these signallin...
Autores principales: | Corbett, Harriet Jane, Connell, Marilyn Gwen, Fernig, David Garth, Losty, Paul Damion, Jesudason, Edwin Chitran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335125/ https://www.ncbi.nlm.nih.gov/pubmed/22539968 http://dx.doi.org/10.1371/journal.pone.0035364 |
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