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Ets-1 Is Essential for Connective Tissue Growth Factor (CTGF/CCN2) Induction by TGF-β1 in Osteoblasts

BACKGROUND: Ets-1 controls osteoblast differentiation and bone development; however, its downstream mechanism of action in osteoblasts remains largely undetermined. CCN2 acts as an anabolic growth factor to regulate osteoblast differentiation and function. CCN2 is induced by TGF-β1 and acts as a med...

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Detalles Bibliográficos
Autores principales:	Geisinger, Max T., Astaiza, Randy, Butler, Tiffany, Popoff, Steven N., Planey, Sonia Lobo, Arnott, John A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335151/ https://www.ncbi.nlm.nih.gov/pubmed/22539964 http://dx.doi.org/10.1371/journal.pone.0035258

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