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AMELIORATION OF MERCURIC CHLORIDE INDUCED NEPHROTOXICITY AND OXIDATIVE STRESS BY GARLIC EXTRACT
Effect of Garlic against mercuric chloride induced toxicity in albino rats was studied. Oral administration of mercuric chloride (100mg/kg/p.o) for 30 days resulted in significant increase in LPO Basal level and LPO FeSO(4) induced and significant decrease in GSH (Glutathione) and Vit C as compared...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335234/ https://www.ncbi.nlm.nih.gov/pubmed/22557228 |
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author | Abirami, N. Jagadeeswari, R. |
author_facet | Abirami, N. Jagadeeswari, R. |
author_sort | Abirami, N. |
collection | PubMed |
description | Effect of Garlic against mercuric chloride induced toxicity in albino rats was studied. Oral administration of mercuric chloride (100mg/kg/p.o) for 30 days resulted in significant increase in LPO Basal level and LPO FeSO(4) induced and significant decrease in GSH (Glutathione) and Vit C as compared to the normal and control group. Simultaneous administration of Garlic along with Mercuric chloride, produced a pronounced neproprotective effect against mercuric chloride induced toxicity in rats by restoring the normal levels of biochemical parameters. |
format | Online Article Text |
id | pubmed-3335234 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33352342012-04-27 AMELIORATION OF MERCURIC CHLORIDE INDUCED NEPHROTOXICITY AND OXIDATIVE STRESS BY GARLIC EXTRACT Abirami, N. Jagadeeswari, R. Anc Sci Life Original Article Effect of Garlic against mercuric chloride induced toxicity in albino rats was studied. Oral administration of mercuric chloride (100mg/kg/p.o) for 30 days resulted in significant increase in LPO Basal level and LPO FeSO(4) induced and significant decrease in GSH (Glutathione) and Vit C as compared to the normal and control group. Simultaneous administration of Garlic along with Mercuric chloride, produced a pronounced neproprotective effect against mercuric chloride induced toxicity in rats by restoring the normal levels of biochemical parameters. Medknow Publications & Media Pvt Ltd 2006 /pmc/articles/PMC3335234/ /pubmed/22557228 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Abirami, N. Jagadeeswari, R. AMELIORATION OF MERCURIC CHLORIDE INDUCED NEPHROTOXICITY AND OXIDATIVE STRESS BY GARLIC EXTRACT |
title | AMELIORATION OF MERCURIC CHLORIDE INDUCED NEPHROTOXICITY AND OXIDATIVE STRESS BY GARLIC EXTRACT |
title_full | AMELIORATION OF MERCURIC CHLORIDE INDUCED NEPHROTOXICITY AND OXIDATIVE STRESS BY GARLIC EXTRACT |
title_fullStr | AMELIORATION OF MERCURIC CHLORIDE INDUCED NEPHROTOXICITY AND OXIDATIVE STRESS BY GARLIC EXTRACT |
title_full_unstemmed | AMELIORATION OF MERCURIC CHLORIDE INDUCED NEPHROTOXICITY AND OXIDATIVE STRESS BY GARLIC EXTRACT |
title_short | AMELIORATION OF MERCURIC CHLORIDE INDUCED NEPHROTOXICITY AND OXIDATIVE STRESS BY GARLIC EXTRACT |
title_sort | amelioration of mercuric chloride induced nephrotoxicity and oxidative stress by garlic extract |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335234/ https://www.ncbi.nlm.nih.gov/pubmed/22557228 |
work_keys_str_mv | AT abiramin ameliorationofmercuricchlorideinducednephrotoxicityandoxidativestressbygarlicextract AT jagadeeswarir ameliorationofmercuricchlorideinducednephrotoxicityandoxidativestressbygarlicextract |