COMPARATIVE ANTI – MICROBIAL EVALUATION STUDIES OF THE EXTRACTS AND ISOLATES OF LEAVES & BARK OF WRIGHTIA TOMENTOSA

The Butanol and Ethanol extract of the leaves and bark of Wrightia tomentosa along with its seven pure component isolates (BLF(28), BLF (29*), BBF(29), ELF(3), ELF7, ELF(17*), EBF(7) ) after fractionation by column chromatography were evaluated for antimicrobial activity against Gram positive (S. au...

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Detalles Bibliográficos
Autores principales: Nagarajan, K., Mazumder, Avijit, Ghosh, L.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2006
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335240/
https://www.ncbi.nlm.nih.gov/pubmed/22557219
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author Nagarajan, K.
Mazumder, Avijit
Ghosh, L.K.
author_facet Nagarajan, K.
Mazumder, Avijit
Ghosh, L.K.
author_sort Nagarajan, K.
collection PubMed
description The Butanol and Ethanol extract of the leaves and bark of Wrightia tomentosa along with its seven pure component isolates (BLF(28), BLF (29*), BBF(29), ELF(3), ELF7, ELF(17*), EBF(7) ) after fractionation by column chromatography were evaluated for antimicrobial activity against Gram positive (S. aureus, S. fecalis, S.albus and B.subtilis) and Gram negative (Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris & Klebsiella aerogenes) bacteria and the fungi Candida albicans by disc diffusion method. The extracts and isolates showed different degree of activity against pathogenic microbes. The results obtained were compared with standard drugs Ciprofloxacin (10μg) and Clotrimazole (10μg). The isolates of butanol bark extract (BBF(29)) followed by leaf extract(BLF(29*)) were considerably more effective than the ethanol leaf and bark extract in inhibiting all the microbial strains
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spelling pubmed-33352402012-04-27 COMPARATIVE ANTI – MICROBIAL EVALUATION STUDIES OF THE EXTRACTS AND ISOLATES OF LEAVES & BARK OF WRIGHTIA TOMENTOSA Nagarajan, K. Mazumder, Avijit Ghosh, L.K. Anc Sci Life Original Article The Butanol and Ethanol extract of the leaves and bark of Wrightia tomentosa along with its seven pure component isolates (BLF(28), BLF (29*), BBF(29), ELF(3), ELF7, ELF(17*), EBF(7) ) after fractionation by column chromatography were evaluated for antimicrobial activity against Gram positive (S. aureus, S. fecalis, S.albus and B.subtilis) and Gram negative (Escherichia coli, Pseudomonas aeruginosa, Proteus vulgaris & Klebsiella aerogenes) bacteria and the fungi Candida albicans by disc diffusion method. The extracts and isolates showed different degree of activity against pathogenic microbes. The results obtained were compared with standard drugs Ciprofloxacin (10μg) and Clotrimazole (10μg). The isolates of butanol bark extract (BBF(29)) followed by leaf extract(BLF(29*)) were considerably more effective than the ethanol leaf and bark extract in inhibiting all the microbial strains Medknow Publications & Media Pvt Ltd 2006 /pmc/articles/PMC3335240/ /pubmed/22557219 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Nagarajan, K.
Mazumder, Avijit
Ghosh, L.K.
COMPARATIVE ANTI – MICROBIAL EVALUATION STUDIES OF THE EXTRACTS AND ISOLATES OF LEAVES & BARK OF WRIGHTIA TOMENTOSA
title COMPARATIVE ANTI – MICROBIAL EVALUATION STUDIES OF THE EXTRACTS AND ISOLATES OF LEAVES & BARK OF WRIGHTIA TOMENTOSA
title_full COMPARATIVE ANTI – MICROBIAL EVALUATION STUDIES OF THE EXTRACTS AND ISOLATES OF LEAVES & BARK OF WRIGHTIA TOMENTOSA
title_fullStr COMPARATIVE ANTI – MICROBIAL EVALUATION STUDIES OF THE EXTRACTS AND ISOLATES OF LEAVES & BARK OF WRIGHTIA TOMENTOSA
title_full_unstemmed COMPARATIVE ANTI – MICROBIAL EVALUATION STUDIES OF THE EXTRACTS AND ISOLATES OF LEAVES & BARK OF WRIGHTIA TOMENTOSA
title_short COMPARATIVE ANTI – MICROBIAL EVALUATION STUDIES OF THE EXTRACTS AND ISOLATES OF LEAVES & BARK OF WRIGHTIA TOMENTOSA
title_sort comparative anti – microbial evaluation studies of the extracts and isolates of leaves & bark of wrightia tomentosa
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335240/
https://www.ncbi.nlm.nih.gov/pubmed/22557219
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AT ghoshlk comparativeantimicrobialevaluationstudiesoftheextractsandisolatesofleavesbarkofwrightiatomentosa

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