Cargando…

Paraoxonases-2 and -3 Are Important Defense Enzymes against Pseudomonas aeruginosa Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties

The pathogen Pseudomonas aeruginosa causes serious damage in immunocompromised patients by secretion of various virulence factors, among them the quorum sensing N-(3-oxododecanoyl)-L-homoserine lactone (3OC12) and the redox-active pyocyanin (PCN). Paraoxonase-2 (PON2) may protect against P. aerugino...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schweikert, Eva-Maria, Amort, Julianna, Wilgenbus, Petra, Förstermann, Ulrich, Teiber, John F., Horke, Sven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335252/ https://www.ncbi.nlm.nih.gov/pubmed/22570791 http://dx.doi.org/10.1155/2012/352857

Ejemplares similares

The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients
por: Krüger, Maximilian, et al.
Publicado: (2016)

Beyond reduction of atherosclerosis: PON2 provides apoptosis resistance and stabilizes tumor cells
por: Witte, I, et al.
Publicado: (2011)

Antibacterial and anti-virulence effects of furazolidone on Trueperella pyogenes and Pseudomonas aeruginosa
por: Chen, Qin, et al.
Publicado: (2022)

Core defense hotspots within Pseudomonas aeruginosa are a consistent and rich source of anti-phage defense systems
por: Johnson, Matthew C, et al.
Publicado: (2023)

Reducing the virulence of Pseudomonas aeruginosa by using multiple quorum-quenching enzymes
por: Khatun, Mst Afroza, et al.
Publicado: (2023)

Additive Effects of Quorum Sensing Anti-Activators on Pseudomonas aeruginosa Virulence Traits and Transcriptome
por: Asfahl, Kyle L., et al.
Publicado: (2018)

Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy
por: Singh, Vijay K., et al.
Publicado: (2022)

Anti‐biofilm and anti‐virulence effects of silica oxide nanoparticle–conjugation of lectin purified from Pseudomonas aeruginosa
por: Nsayef Muslim, Sahira, et al.
Publicado: (2021)

Expression of PPARγ and Paraoxonase 2 Correlated with Pseudomonas aeruginosa Infection in Cystic Fibrosis
por: Griffin, Phoebe E., et al.
Publicado: (2012)

oprC Impairs Host Defense by Increasing the Quorum-Sensing-Mediated Virulence of Pseudomonas aeruginosa
por: Gao, Pan, et al.
Publicado: (2020)

Repurposing phytochemicals as anti‐virulent agents to attenuate quorum sensing‐regulated virulence factors and biofilm formation in Pseudomonas aeruginosa
por: Chadha, Jatin, et al.
Publicado: (2021)

Exploring Oceans for Curative Compounds: Potential New Antimicrobial and Anti-Virulence Molecules against Pseudomonas aeruginosa
por: Coppola, Daniela, et al.
Publicado: (2022)

Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa
por: Borgert, Sebastian Roman, et al.
Publicado: (2022)

Anti-Biofilm Enzymes-Assisted Antibiotic Therapy against Burn Wound Infection by Pseudomonas aeruginosa
por: Zhang, Yixin, et al.
Publicado: (2023)

Human Host Defense Peptide LL-37 Stimulates Virulence Factor Production and Adaptive Resistance in Pseudomonas aeruginosa
por: Strempel, Nikola, et al.
Publicado: (2013)

Evidence for Direct Control of Virulence and Defense Gene Circuits by the Pseudomonas aeruginosa Quorum Sensing Regulator, MvfR
por: Maura, Damien, et al.
Publicado: (2016)

Tetradecanoic Acids With Anti-Virulence Properties Increase the Pathogenicity of Pseudomonas aeruginosa in a Murine Cutaneous Infection Model
por: Juárez-Rodríguez, Martha María, et al.
Publicado: (2021)

Evaluation of the antibacterial, antibiofilm, and anti-virulence effects of acetic acid and the related mechanisms on colistin-resistant Pseudomonas aeruginosa
por: Feng, Luozhu, et al.
Publicado: (2022)

Cooperation and virulence in acute Pseudomonas aeruginosa infections
por: Harrison, Freya, et al.
Publicado: (2006)

NADH Dehydrogenases in Pseudomonas aeruginosa Growth and Virulence
por: Torres, Angela, et al.
Publicado: (2019)

Exoproteomics for Better Understanding Pseudomonas aeruginosa Virulence
por: Sauvage, Salomé, et al.
Publicado: (2020)

Sodium Citrate Alleviates Virulence in Pseudomonas aeruginosa
por: Khayat, Maan T., et al.
Publicado: (2022)

Transcriptional Regulators Controlling Virulence in Pseudomonas aeruginosa
por: Sánchez-Jiménez, Ana, et al.
Publicado: (2023)

Anti-quorum Sensing and Anti-biofilm Activity of Delftia tsuruhatensis Extract by Attenuating the Quorum Sensing-Controlled Virulence Factor Production in Pseudomonas aeruginosa
por: Singh, Vijay K., et al.
Publicado: (2017)

Comprehensive Host Cell-Based Screening Assays for Identification of Anti-Virulence Drugs Targeting Pseudomonas aeruginosa and Salmonella Typhimurium
por: von Ambüren, Julia, et al.
Publicado: (2020)

Corrigendum: Anti-quorum Sensing and Anti-biofilm Activity of Delftia tsuruhatensis Extract by Attenuating the Quorum Sensing-Controlled Virulence Factor Production in Pseudomonas aeruginosa
por: Singh, Vijay K., et al.
Publicado: (2019)

Genomic analysis reveals that Pseudomonas aeruginosa virulence is combinatorial
por: Lee, Daniel G, et al.
Publicado: (2006)

Differentiation in Quinolone Resistance by Virulence Genotype in Pseudomonas aeruginosa
por: Agnello, Melissa, et al.
Publicado: (2012)

Indole and 7‐hydroxyindole diminish Pseudomonas aeruginosa virulence
por: Lee, Jintae, et al.
Publicado: (2009)

The Lon Protease Is Essential for Full Virulence in Pseudomonas aeruginosa
por: Breidenstein, Elena B. M., et al.
Publicado: (2012)

Regulation of Pseudomonas aeruginosa Virulence by Distinct Iron Sources
por: Reinhart, Alexandria A., et al.
Publicado: (2016)

Exolysin Shapes the Virulence of Pseudomonas aeruginosa Clonal Outliers
por: Reboud, Emeline, et al.
Publicado: (2017)

Two-component systems required for virulence in Pseudomonas aeruginosa
por: Francis, Vanessa I., et al.
Publicado: (2017)

Mucin glycans attenuate the virulence of Pseudomonas aeruginosa in infection
por: Wheeler, Kelsey M., et al.
Publicado: (2019)

Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence
por: Sultan, Maria, et al.
Publicado: (2021)

Sub-Inhibitory Antibiotic Exposure and Virulence in Pseudomonas aeruginosa
por: Nolan, Charlotte, et al.
Publicado: (2021)

An Organ System-Based Synopsis of Pseudomonas aeruginosa Virulence
por: Morin, Charles D., et al.
Publicado: (2021)

Tackling Virulence of Pseudomonas aeruginosa by the Natural Furanone Sotolon
por: Aldawsari, Mohammed F., et al.
Publicado: (2021)

Attenuation of Pseudomonas aeruginosa Virulence by Pomegranate Peel Extract
por: Peppoloni, Samuele, et al.
Publicado: (2022)

Copper selects for siderophore-mediated virulence in Pseudomonas aeruginosa
por: Lear, Luke, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mjdrtm5glrkhun9c9e1kamrqeo