Apo A1 Mimetic Rescues the Diabetic Phenotype of HO-2 Knockout Mice via an Increase in HO-1 Adiponectin and LKBI Signaling Pathway

Insulin resistance, with adipose tissue dysfunction, is one of the hallmarks of metabolic syndrome. We have reported a metabolic syndrome-like phenotype in heme oxygenase (HO)-2 knockout mice, which presented with concurrent HO-1 deficiency and were amenable to rescue by an EET analog. Apo A-I mimet...

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Detalles Bibliográficos
Autores principales: Cao, Jian, Puri, Nitin, Sodhi, Komal, Bellner, Lars, Abraham, Nader G., Kappas, Attallah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335301/
https://www.ncbi.nlm.nih.gov/pubmed/22577519
http://dx.doi.org/10.1155/2012/628147

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