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Fibrosarcoma of Mandible: A Case Report

Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects the oral cavity and can cause local recurrences or metastasis. In this paper, a case of fibrosarcoma in the posterior area of mandible in a 44-year-old woman is described. Clinical examination revealed a growth on ri...

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Detalles Bibliográficos
Autores principales: Yuwanati, Monal B., Tupkari, J. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335480/
https://www.ncbi.nlm.nih.gov/pubmed/22567441
http://dx.doi.org/10.1155/2011/536086
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author Yuwanati, Monal B.
Tupkari, J. V.
author_facet Yuwanati, Monal B.
Tupkari, J. V.
author_sort Yuwanati, Monal B.
collection PubMed
description Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects the oral cavity and can cause local recurrences or metastasis. In this paper, a case of fibrosarcoma in the posterior area of mandible in a 44-year-old woman is described. Clinical examination revealed a growth on right mandibular third molar region extending on the buccal and the lingual side. There was history of extraction of posterior teeth. Radiologically, there was a diffuse bone loss. Microscopically, the tumor showed an intense proliferation of fibroblasts of variable size and shape. These cells were arranged in parallel bands and partly crossing each other. The cells exhibited increased mitotic activity and nuclear pleomorphism. Immunohistochemically the cells showed immunoreactivity only for vimentin while they exhibited negativity towards S-100 protein, cytokeratin cocktail, HMB-45, desmin, smooth muscle actin, and epithelial membrane antigen (EMA). Based on findings the final diagnosis of fibrosarcoma was made.
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spelling pubmed-33354802012-05-07 Fibrosarcoma of Mandible: A Case Report Yuwanati, Monal B. Tupkari, J. V. Case Rep Dent Case Report Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects the oral cavity and can cause local recurrences or metastasis. In this paper, a case of fibrosarcoma in the posterior area of mandible in a 44-year-old woman is described. Clinical examination revealed a growth on right mandibular third molar region extending on the buccal and the lingual side. There was history of extraction of posterior teeth. Radiologically, there was a diffuse bone loss. Microscopically, the tumor showed an intense proliferation of fibroblasts of variable size and shape. These cells were arranged in parallel bands and partly crossing each other. The cells exhibited increased mitotic activity and nuclear pleomorphism. Immunohistochemically the cells showed immunoreactivity only for vimentin while they exhibited negativity towards S-100 protein, cytokeratin cocktail, HMB-45, desmin, smooth muscle actin, and epithelial membrane antigen (EMA). Based on findings the final diagnosis of fibrosarcoma was made. Hindawi Publishing Corporation 2011 2011-07-07 /pmc/articles/PMC3335480/ /pubmed/22567441 http://dx.doi.org/10.1155/2011/536086 Text en Copyright © 2011 M. B. Yuwanati and J. V. Tupkari. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Yuwanati, Monal B.
Tupkari, J. V.
Fibrosarcoma of Mandible: A Case Report
title Fibrosarcoma of Mandible: A Case Report
title_full Fibrosarcoma of Mandible: A Case Report
title_fullStr Fibrosarcoma of Mandible: A Case Report
title_full_unstemmed Fibrosarcoma of Mandible: A Case Report
title_short Fibrosarcoma of Mandible: A Case Report
title_sort fibrosarcoma of mandible: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335480/
https://www.ncbi.nlm.nih.gov/pubmed/22567441
http://dx.doi.org/10.1155/2011/536086
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