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Fibrosarcoma of Mandible: A Case Report
Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects the oral cavity and can cause local recurrences or metastasis. In this paper, a case of fibrosarcoma in the posterior area of mandible in a 44-year-old woman is described. Clinical examination revealed a growth on ri...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335480/ https://www.ncbi.nlm.nih.gov/pubmed/22567441 http://dx.doi.org/10.1155/2011/536086 |
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author | Yuwanati, Monal B. Tupkari, J. V. |
author_facet | Yuwanati, Monal B. Tupkari, J. V. |
author_sort | Yuwanati, Monal B. |
collection | PubMed |
description | Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects the oral cavity and can cause local recurrences or metastasis. In this paper, a case of fibrosarcoma in the posterior area of mandible in a 44-year-old woman is described. Clinical examination revealed a growth on right mandibular third molar region extending on the buccal and the lingual side. There was history of extraction of posterior teeth. Radiologically, there was a diffuse bone loss. Microscopically, the tumor showed an intense proliferation of fibroblasts of variable size and shape. These cells were arranged in parallel bands and partly crossing each other. The cells exhibited increased mitotic activity and nuclear pleomorphism. Immunohistochemically the cells showed immunoreactivity only for vimentin while they exhibited negativity towards S-100 protein, cytokeratin cocktail, HMB-45, desmin, smooth muscle actin, and epithelial membrane antigen (EMA). Based on findings the final diagnosis of fibrosarcoma was made. |
format | Online Article Text |
id | pubmed-3335480 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33354802012-05-07 Fibrosarcoma of Mandible: A Case Report Yuwanati, Monal B. Tupkari, J. V. Case Rep Dent Case Report Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects the oral cavity and can cause local recurrences or metastasis. In this paper, a case of fibrosarcoma in the posterior area of mandible in a 44-year-old woman is described. Clinical examination revealed a growth on right mandibular third molar region extending on the buccal and the lingual side. There was history of extraction of posterior teeth. Radiologically, there was a diffuse bone loss. Microscopically, the tumor showed an intense proliferation of fibroblasts of variable size and shape. These cells were arranged in parallel bands and partly crossing each other. The cells exhibited increased mitotic activity and nuclear pleomorphism. Immunohistochemically the cells showed immunoreactivity only for vimentin while they exhibited negativity towards S-100 protein, cytokeratin cocktail, HMB-45, desmin, smooth muscle actin, and epithelial membrane antigen (EMA). Based on findings the final diagnosis of fibrosarcoma was made. Hindawi Publishing Corporation 2011 2011-07-07 /pmc/articles/PMC3335480/ /pubmed/22567441 http://dx.doi.org/10.1155/2011/536086 Text en Copyright © 2011 M. B. Yuwanati and J. V. Tupkari. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Yuwanati, Monal B. Tupkari, J. V. Fibrosarcoma of Mandible: A Case Report |
title | Fibrosarcoma of Mandible: A Case Report |
title_full | Fibrosarcoma of Mandible: A Case Report |
title_fullStr | Fibrosarcoma of Mandible: A Case Report |
title_full_unstemmed | Fibrosarcoma of Mandible: A Case Report |
title_short | Fibrosarcoma of Mandible: A Case Report |
title_sort | fibrosarcoma of mandible: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335480/ https://www.ncbi.nlm.nih.gov/pubmed/22567441 http://dx.doi.org/10.1155/2011/536086 |
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