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How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways
Satellites are one of the most enigmatic parts of the eukaryotic genome. These highly repetitive, noncoding sequences make up as much as half or more of the genomic content and are known to play essential roles in chromosome segregation during meiosis and mitosis, yet they evolve rapidly between clo...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335601/ https://www.ncbi.nlm.nih.gov/pubmed/22567387 http://dx.doi.org/10.1155/2012/430136 |
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author | Ferree, Patrick M. Prasad, Satyaki |
author_facet | Ferree, Patrick M. Prasad, Satyaki |
author_sort | Ferree, Patrick M. |
collection | PubMed |
description | Satellites are one of the most enigmatic parts of the eukaryotic genome. These highly repetitive, noncoding sequences make up as much as half or more of the genomic content and are known to play essential roles in chromosome segregation during meiosis and mitosis, yet they evolve rapidly between closely related species. Research over the last several decades has revealed that satellite divergence can serve as a formidable reproductive barrier between sibling species. Here we highlight several key studies on Drosophila and other model organisms demonstrating deleterious effects of satellites and their rapid evolution on the structure and function of chromosomes in interspecies hybrids. These studies demonstrate that satellites can impact chromosomes at a number of different developmental stages and through distinct cellular mechanisms, including heterochromatin formation. These findings have important implications for how loci that cause postzygotic reproductive isolation are viewed. |
format | Online Article Text |
id | pubmed-3335601 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-33356012012-05-07 How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways Ferree, Patrick M. Prasad, Satyaki Genet Res Int Review Article Satellites are one of the most enigmatic parts of the eukaryotic genome. These highly repetitive, noncoding sequences make up as much as half or more of the genomic content and are known to play essential roles in chromosome segregation during meiosis and mitosis, yet they evolve rapidly between closely related species. Research over the last several decades has revealed that satellite divergence can serve as a formidable reproductive barrier between sibling species. Here we highlight several key studies on Drosophila and other model organisms demonstrating deleterious effects of satellites and their rapid evolution on the structure and function of chromosomes in interspecies hybrids. These studies demonstrate that satellites can impact chromosomes at a number of different developmental stages and through distinct cellular mechanisms, including heterochromatin formation. These findings have important implications for how loci that cause postzygotic reproductive isolation are viewed. Hindawi Publishing Corporation 2012 2012-01-29 /pmc/articles/PMC3335601/ /pubmed/22567387 http://dx.doi.org/10.1155/2012/430136 Text en Copyright © 2012 P. M. Ferree and S. Prasad. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Ferree, Patrick M. Prasad, Satyaki How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways |
title | How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways |
title_full | How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways |
title_fullStr | How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways |
title_full_unstemmed | How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways |
title_short | How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways |
title_sort | how can satellite dna divergence cause reproductive isolation? let us count the chromosomal ways |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335601/ https://www.ncbi.nlm.nih.gov/pubmed/22567387 http://dx.doi.org/10.1155/2012/430136 |
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