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How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways

Satellites are one of the most enigmatic parts of the eukaryotic genome. These highly repetitive, noncoding sequences make up as much as half or more of the genomic content and are known to play essential roles in chromosome segregation during meiosis and mitosis, yet they evolve rapidly between clo...

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Detalles Bibliográficos
Autores principales: Ferree, Patrick M., Prasad, Satyaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335601/
https://www.ncbi.nlm.nih.gov/pubmed/22567387
http://dx.doi.org/10.1155/2012/430136
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author Ferree, Patrick M.
Prasad, Satyaki
author_facet Ferree, Patrick M.
Prasad, Satyaki
author_sort Ferree, Patrick M.
collection PubMed
description Satellites are one of the most enigmatic parts of the eukaryotic genome. These highly repetitive, noncoding sequences make up as much as half or more of the genomic content and are known to play essential roles in chromosome segregation during meiosis and mitosis, yet they evolve rapidly between closely related species. Research over the last several decades has revealed that satellite divergence can serve as a formidable reproductive barrier between sibling species. Here we highlight several key studies on Drosophila and other model organisms demonstrating deleterious effects of satellites and their rapid evolution on the structure and function of chromosomes in interspecies hybrids. These studies demonstrate that satellites can impact chromosomes at a number of different developmental stages and through distinct cellular mechanisms, including heterochromatin formation. These findings have important implications for how loci that cause postzygotic reproductive isolation are viewed.
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spelling pubmed-33356012012-05-07 How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways Ferree, Patrick M. Prasad, Satyaki Genet Res Int Review Article Satellites are one of the most enigmatic parts of the eukaryotic genome. These highly repetitive, noncoding sequences make up as much as half or more of the genomic content and are known to play essential roles in chromosome segregation during meiosis and mitosis, yet they evolve rapidly between closely related species. Research over the last several decades has revealed that satellite divergence can serve as a formidable reproductive barrier between sibling species. Here we highlight several key studies on Drosophila and other model organisms demonstrating deleterious effects of satellites and their rapid evolution on the structure and function of chromosomes in interspecies hybrids. These studies demonstrate that satellites can impact chromosomes at a number of different developmental stages and through distinct cellular mechanisms, including heterochromatin formation. These findings have important implications for how loci that cause postzygotic reproductive isolation are viewed. Hindawi Publishing Corporation 2012 2012-01-29 /pmc/articles/PMC3335601/ /pubmed/22567387 http://dx.doi.org/10.1155/2012/430136 Text en Copyright © 2012 P. M. Ferree and S. Prasad. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Ferree, Patrick M.
Prasad, Satyaki
How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways
title How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways
title_full How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways
title_fullStr How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways
title_full_unstemmed How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways
title_short How Can Satellite DNA Divergence Cause Reproductive Isolation? Let Us Count the Chromosomal Ways
title_sort how can satellite dna divergence cause reproductive isolation? let us count the chromosomal ways
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335601/
https://www.ncbi.nlm.nih.gov/pubmed/22567387
http://dx.doi.org/10.1155/2012/430136
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