miR-125b Promotes Early Germ Layer Specification through Lin28/let-7d and Preferential Differentiation of Mesoderm in Human Embryonic Stem Cells

Unlike other essential organs, the heart does not undergo tissue repair following injury. Human embryonic stem cells (hESCs) grow indefinitely in culture while maintaining the ability to differentiate into many tissues of the body. As such, they provide a unique opportunity to explore the mechanisms...

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Detalles Bibliográficos
Autores principales: Wong, Sharon S. Y., Ritner, Carissa, Ramachandran, Sweta, Aurigui, Julian, Pitt, Cameron, Chandra, Piyanka, Ling, Vivian B., Yabut, Odessa, Bernstein, Harold S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335794/
https://www.ncbi.nlm.nih.gov/pubmed/22545159
http://dx.doi.org/10.1371/journal.pone.0036121

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