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The Hepatitis E Virus Polyproline Region Is Involved in Viral Adaptation
Genomes of hepatitis E virus (HEV), rubivirus and cutthroat virus (CTV) contain a region of high proline density and low amino acid (aa) complexity, named the polyproline region (PPR). In HEV genotypes 1, 3 and 4, it is the only region within the non-structural open reading frame (ORF1) with positiv...
Autores principales: | Purdy, Michael A., Lara, James, Khudyakov, Yury E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335810/ https://www.ncbi.nlm.nih.gov/pubmed/22545153 http://dx.doi.org/10.1371/journal.pone.0035974 |
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