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Differential Modulation of Retinal Degeneration by Ccl2 and Cx3cr1 Chemokine Signalling
Microglia and macrophages are recruited to sites of retinal degeneration where local cytokines and chemokines determine protective or neurotoxic microglia responses. Defining the role of Ccl2-Ccr2 and Cx3cl1-Cx3cr1 signalling for retinal pathology is of particular interest because of its potential r...
Autores principales: | Luhmann, Ulrich F. O., Lange, Clemens A., Robbie, Scott, Munro, Peter M. G., Cowing, Jill A., Armer, Hannah E. J., Luong, Vy, Carvalho, Livia S., MacLaren, Robert E., Fitzke, Frederick W., Bainbridge, James W. B., Ali, Robin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335860/ https://www.ncbi.nlm.nih.gov/pubmed/22545116 http://dx.doi.org/10.1371/journal.pone.0035551 |
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