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Sialyllactose in Viral Membrane Gangliosides Is a Novel Molecular Recognition Pattern for Mature Dendritic Cell Capture of HIV-1
HIV-1 is internalized into mature dendritic cells (mDCs) via an as yet undefined mechanism with subsequent transfer of stored, infectious virus to CD4(+) T lymphocytes. Thus, HIV-1 subverts a DC antigen capture mechanism to promote viral spread. Here, we show that gangliosides in the HIV-1 membrane...
Autores principales: | Izquierdo-Useros, Nuria, Lorizate, Maier, Contreras, F.-Xabier, Rodriguez-Plata, Maria T., Glass, Bärbel, Erkizia, Itziar, Prado, Julia G., Casas, Josefina, Fabriàs, Gemma, Kräusslich, Hans-Georg, Martinez-Picado, Javier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3335875/ https://www.ncbi.nlm.nih.gov/pubmed/22545022 http://dx.doi.org/10.1371/journal.pbio.1001315 |
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