Tramadol Pretreatment Enhances Ketamine-Induced Antidepressant Effects and Increases Mammalian Target of Rapamycin in Rat Hippocampus and Prefrontal Cortex

Several lines of evidence have demonstrated that acute administration of ketamine elicits fast-acting antidepressant effects. Moreover, tramadol also has potential antidepressant effects. The aim of this study was to investigate the effects of pretreatment with tramadol on ketamine-induced antidepre...

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Detalles Bibliográficos
Autores principales: Yang, Chun, Li, Wen-Yuan, Yu, Hai-Yin, Gao, Zhi-Qin, Liu, Xiang-Liu, Zhou, Zhi-Qiang, Yang, Jian-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336144/
https://www.ncbi.nlm.nih.gov/pubmed/22577289
http://dx.doi.org/10.1155/2012/175619

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