Cargando…

Invitro Antioxidant Activity of Selected Antiasthmatic Herbal Constituents

Asthmatic patients are more subjected to continuous oxidative stress. Roosting the antioxidant defenses of asthma patient could be beneficial as it may help thwart symptoms of the lung disease and asthma. Considering these facts different plant extracts and phytoconstituents with proven anti asthmat...

Descripción completa

Detalles Bibliográficos
Autores principales: Nilani, P., Kasthuribai, N., Duraisamy, B., Dhamodaran, P., Ravichandran, S., Ilango, K., Suresh, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336331/
https://www.ncbi.nlm.nih.gov/pubmed/22557323
_version_ 1782230914198142976
author Nilani, P.
Kasthuribai, N.
Duraisamy, B.
Dhamodaran, P.
Ravichandran, S.
Ilango, K.
Suresh, B.
author_facet Nilani, P.
Kasthuribai, N.
Duraisamy, B.
Dhamodaran, P.
Ravichandran, S.
Ilango, K.
Suresh, B.
author_sort Nilani, P.
collection PubMed
description Asthmatic patients are more subjected to continuous oxidative stress. Roosting the antioxidant defenses of asthma patient could be beneficial as it may help thwart symptoms of the lung disease and asthma. Considering these facts different plant extracts and phytoconstituents with proven anti asthmatic property had been subjected to antioxidant study at various combinations using Diphenyl Vicryl Hydrazyl radical scavenging method, Hydrogen Peroxide radical scavenging method, Nitric oxide radical inhibition method, ABTS radical scavenging method and Lipid peroxidation assay method. All the selected herbal based constituents and extracts at different combination showed a potent antioxidant activiy by Nitric oxide radical inhibition activiy method followed by ABTS method. The present finding suggests that the selected plant based anti asthmatic constituents namely Coleus extract (10% Forskolin), Piper longum extract (20% Piperine), CurcuminC3Complex (60% Curcumin), Vasaka (30% Vasicinone), Forskolin (95%), Pperine (98%), Curcumin C3 Complex (98.5%) and Vasicinone (75%) could be utilised in alternate anti asthmatic therapy, since they play a vital role in scavenging Nitric oxide which could prevent the bronchial inflammation in asthmatic patients.
format Online
Article
Text
id pubmed-3336331
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-33363312012-04-27 Invitro Antioxidant Activity of Selected Antiasthmatic Herbal Constituents Nilani, P. Kasthuribai, N. Duraisamy, B. Dhamodaran, P. Ravichandran, S. Ilango, K. Suresh, B. Anc Sci Life Original Article Asthmatic patients are more subjected to continuous oxidative stress. Roosting the antioxidant defenses of asthma patient could be beneficial as it may help thwart symptoms of the lung disease and asthma. Considering these facts different plant extracts and phytoconstituents with proven anti asthmatic property had been subjected to antioxidant study at various combinations using Diphenyl Vicryl Hydrazyl radical scavenging method, Hydrogen Peroxide radical scavenging method, Nitric oxide radical inhibition method, ABTS radical scavenging method and Lipid peroxidation assay method. All the selected herbal based constituents and extracts at different combination showed a potent antioxidant activiy by Nitric oxide radical inhibition activiy method followed by ABTS method. The present finding suggests that the selected plant based anti asthmatic constituents namely Coleus extract (10% Forskolin), Piper longum extract (20% Piperine), CurcuminC3Complex (60% Curcumin), Vasaka (30% Vasicinone), Forskolin (95%), Pperine (98%), Curcumin C3 Complex (98.5%) and Vasicinone (75%) could be utilised in alternate anti asthmatic therapy, since they play a vital role in scavenging Nitric oxide which could prevent the bronchial inflammation in asthmatic patients. Medknow Publications & Media Pvt Ltd 2009 /pmc/articles/PMC3336331/ /pubmed/22557323 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Nilani, P.
Kasthuribai, N.
Duraisamy, B.
Dhamodaran, P.
Ravichandran, S.
Ilango, K.
Suresh, B.
Invitro Antioxidant Activity of Selected Antiasthmatic Herbal Constituents
title Invitro Antioxidant Activity of Selected Antiasthmatic Herbal Constituents
title_full Invitro Antioxidant Activity of Selected Antiasthmatic Herbal Constituents
title_fullStr Invitro Antioxidant Activity of Selected Antiasthmatic Herbal Constituents
title_full_unstemmed Invitro Antioxidant Activity of Selected Antiasthmatic Herbal Constituents
title_short Invitro Antioxidant Activity of Selected Antiasthmatic Herbal Constituents
title_sort invitro antioxidant activity of selected antiasthmatic herbal constituents
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336331/
https://www.ncbi.nlm.nih.gov/pubmed/22557323
work_keys_str_mv AT nilanip invitroantioxidantactivityofselectedantiasthmaticherbalconstituents
AT kasthuribain invitroantioxidantactivityofselectedantiasthmaticherbalconstituents
AT duraisamyb invitroantioxidantactivityofselectedantiasthmaticherbalconstituents
AT dhamodaranp invitroantioxidantactivityofselectedantiasthmaticherbalconstituents
AT ravichandrans invitroantioxidantactivityofselectedantiasthmaticherbalconstituents
AT ilangok invitroantioxidantactivityofselectedantiasthmaticherbalconstituents
AT sureshb invitroantioxidantactivityofselectedantiasthmaticherbalconstituents