A Study of hepatoprotective activity of Hedyotis corymbosa. Linn, in albino rats

Hedyotis corymbosa Linn is spreading, suffruticose annual, belongs to family Rubiaceae frequently met with in field through out India, usually during rainy season. This plant is used for their medicinal properties as a folk medicine to treat jaundice, mouth wash in toothache. Hence the present study...

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Autores principales: Chimkode, Rajshekar, Patil, M.B, Jalalpure, Sunil, Pasha, T.Y., sarkar, Sibaji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2009
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336332/
https://www.ncbi.nlm.nih.gov/pubmed/22557330
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author Chimkode, Rajshekar
Patil, M.B
Jalalpure, Sunil
Pasha, T.Y.
sarkar, Sibaji
author_facet Chimkode, Rajshekar
Patil, M.B
Jalalpure, Sunil
Pasha, T.Y.
sarkar, Sibaji
author_sort Chimkode, Rajshekar
collection PubMed
description Hedyotis corymbosa Linn is spreading, suffruticose annual, belongs to family Rubiaceae frequently met with in field through out India, usually during rainy season. This plant is used for their medicinal properties as a folk medicine to treat jaundice, mouth wash in toothache. Hence the present study was aimed to investigate the hepatoprotective activity of ethanolic extract of Hedyotis corymbosa which was separated in to different fractions against carbon tetrachloride intoxification. The results indicate that, Intoxification with CCl(4) increase the levels of SGOT and SGPT. The elevated levels of SGOT and SGPTwere significantly decreased by ether and butanol fractions at P<0.001 and butanone and ethanol at p<0.05, where as petroleum ether and ethyl acetate did not shown any significant reduction in the level of SGOT and SGPT.
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spelling pubmed-33363322012-04-27 A Study of hepatoprotective activity of Hedyotis corymbosa. Linn, in albino rats Chimkode, Rajshekar Patil, M.B Jalalpure, Sunil Pasha, T.Y. sarkar, Sibaji Anc Sci Life Original Article Hedyotis corymbosa Linn is spreading, suffruticose annual, belongs to family Rubiaceae frequently met with in field through out India, usually during rainy season. This plant is used for their medicinal properties as a folk medicine to treat jaundice, mouth wash in toothache. Hence the present study was aimed to investigate the hepatoprotective activity of ethanolic extract of Hedyotis corymbosa which was separated in to different fractions against carbon tetrachloride intoxification. The results indicate that, Intoxification with CCl(4) increase the levels of SGOT and SGPT. The elevated levels of SGOT and SGPTwere significantly decreased by ether and butanol fractions at P<0.001 and butanone and ethanol at p<0.05, where as petroleum ether and ethyl acetate did not shown any significant reduction in the level of SGOT and SGPT. Medknow Publications & Media Pvt Ltd 2009 /pmc/articles/PMC3336332/ /pubmed/22557330 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Chimkode, Rajshekar
Patil, M.B
Jalalpure, Sunil
Pasha, T.Y.
sarkar, Sibaji
A Study of hepatoprotective activity of Hedyotis corymbosa. Linn, in albino rats
title A Study of hepatoprotective activity of Hedyotis corymbosa. Linn, in albino rats
title_full A Study of hepatoprotective activity of Hedyotis corymbosa. Linn, in albino rats
title_fullStr A Study of hepatoprotective activity of Hedyotis corymbosa. Linn, in albino rats
title_full_unstemmed A Study of hepatoprotective activity of Hedyotis corymbosa. Linn, in albino rats
title_short A Study of hepatoprotective activity of Hedyotis corymbosa. Linn, in albino rats
title_sort study of hepatoprotective activity of hedyotis corymbosa. linn, in albino rats
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336332/
https://www.ncbi.nlm.nih.gov/pubmed/22557330
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