Transdermal Diffusion Studies of a Polyherbal Ointment and its tropical therapy

Transdermal diffusion studies of a polyherbal ointment were carried out in vito using franz- Diffusion cell and microbial one inhibition diameter as drug release monitoring parameters. Out of the three ointment base prepared, (Hydrocarbon Base (HB), surfactant Base (SB), Surfactant Base + (Penetrati...

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Autores principales: Reddy, C. Sreenivas, Rammohan, T., Madhu, N., Divaker, M.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336451/
https://www.ncbi.nlm.nih.gov/pubmed/22556925
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author Reddy, C. Sreenivas
Rammohan, T.
Madhu, N.
Divaker, M.C.
author_facet Reddy, C. Sreenivas
Rammohan, T.
Madhu, N.
Divaker, M.C.
author_sort Reddy, C. Sreenivas
collection PubMed
description Transdermal diffusion studies of a polyherbal ointment were carried out in vito using franz- Diffusion cell and microbial one inhibition diameter as drug release monitoring parameters. Out of the three ointment base prepared, (Hydrocarbon Base (HB), surfactant Base (SB), Surfactant Base + (Penetration Enhancer (10 % DMSO) SBPE), we observed that SBPE possesses maximum drug release capacity, as indicated by simultaneous high performance liquid chromatograph (HPLC) and microbial one inhibition monitoring studies. Clinical observations showed at SBPE was effective in cases like infected wounds, scratches and abrasions, infected scabies, pyoderma and furunculosis. The overall cure rate s 79.3% with the antimicro-bial ointmtmtent.
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spelling pubmed-33364512012-04-27 Transdermal Diffusion Studies of a Polyherbal Ointment and its tropical therapy Reddy, C. Sreenivas Rammohan, T. Madhu, N. Divaker, M.C. Anc Sci Life Original Article Transdermal diffusion studies of a polyherbal ointment were carried out in vito using franz- Diffusion cell and microbial one inhibition diameter as drug release monitoring parameters. Out of the three ointment base prepared, (Hydrocarbon Base (HB), surfactant Base (SB), Surfactant Base + (Penetration Enhancer (10 % DMSO) SBPE), we observed that SBPE possesses maximum drug release capacity, as indicated by simultaneous high performance liquid chromatograph (HPLC) and microbial one inhibition monitoring studies. Clinical observations showed at SBPE was effective in cases like infected wounds, scratches and abrasions, infected scabies, pyoderma and furunculosis. The overall cure rate s 79.3% with the antimicro-bial ointmtmtent. Medknow Publications & Media Pvt Ltd 1999 /pmc/articles/PMC3336451/ /pubmed/22556925 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Reddy, C. Sreenivas
Rammohan, T.
Madhu, N.
Divaker, M.C.
Transdermal Diffusion Studies of a Polyherbal Ointment and its tropical therapy
title Transdermal Diffusion Studies of a Polyherbal Ointment and its tropical therapy
title_full Transdermal Diffusion Studies of a Polyherbal Ointment and its tropical therapy
title_fullStr Transdermal Diffusion Studies of a Polyherbal Ointment and its tropical therapy
title_full_unstemmed Transdermal Diffusion Studies of a Polyherbal Ointment and its tropical therapy
title_short Transdermal Diffusion Studies of a Polyherbal Ointment and its tropical therapy
title_sort transdermal diffusion studies of a polyherbal ointment and its tropical therapy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336451/
https://www.ncbi.nlm.nih.gov/pubmed/22556925
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