Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats

Subcutaneous treatment of 50% EtOH extract of neem bark (Azadirachta indica A. juss) to male rats at the dose of 10 mg for 30 days caused arrest of spermatogenesis. The diameter of serminiferous tubule, Leydig cell nucleus and epithelial heights of epididymides were significantly reduced (p≤0.001)....

Descripción completa

Detalles Bibliográficos
Autor principal: Purohit, Ashok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1999
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336455/
https://www.ncbi.nlm.nih.gov/pubmed/22556912
_version_ 1782230936725749760
author Purohit, Ashok
author_facet Purohit, Ashok
author_sort Purohit, Ashok
collection PubMed
description Subcutaneous treatment of 50% EtOH extract of neem bark (Azadirachta indica A. juss) to male rats at the dose of 10 mg for 30 days caused arrest of spermatogenesis. The diameter of serminiferous tubule, Leydig cell nucleus and epithelial heights of epididymides were significantly reduced (p≤0.001). Sperm motility and density were significantly reduced. Reduced testicular and accessory organ protein, sialic acid and vesicular fructose content manifested arrest of spermatogenesis and depletion of androgen level.
format Online
Article
Text
id pubmed-3336455
institution National Center for Biotechnology Information
language English
publishDate 1999
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-33364552012-04-27 Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats Purohit, Ashok Anc Sci Life Original Article Subcutaneous treatment of 50% EtOH extract of neem bark (Azadirachta indica A. juss) to male rats at the dose of 10 mg for 30 days caused arrest of spermatogenesis. The diameter of serminiferous tubule, Leydig cell nucleus and epithelial heights of epididymides were significantly reduced (p≤0.001). Sperm motility and density were significantly reduced. Reduced testicular and accessory organ protein, sialic acid and vesicular fructose content manifested arrest of spermatogenesis and depletion of androgen level. Medknow Publications & Media Pvt Ltd 1999 /pmc/articles/PMC3336455/ /pubmed/22556912 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Purohit, Ashok
Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats
title Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats
title_full Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats
title_fullStr Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats
title_full_unstemmed Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats
title_short Antifertility Efficacy of Neem Bark (Azadirachta indica A.juss.) in Male Rats
title_sort antifertility efficacy of neem bark (azadirachta indica a.juss.) in male rats
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336455/
https://www.ncbi.nlm.nih.gov/pubmed/22556912
work_keys_str_mv AT purohitashok antifertilityefficacyofneembarkazadirachtaindicaajussinmalerats

Ejemplares similares