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EXPERIMENTAL STUDIES ON ARTEMISIA VULGARIS – A POSSIBLE ANTIFERTILITY DRUG
The effect of alcoholic extract of the aerial parts of Artemisia vulgaris Linn on estrous cycle and implantation, in female albino rats, was studied. The drug induced an irregular estrous cycle with random disappearance of estrous phase and increase in the number of metestrus phases within the estro...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
1994
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336493/ https://www.ncbi.nlm.nih.gov/pubmed/22556669 |
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author | Narwaria, A. Khosa, R.L. Dhar, S.K. |
author_facet | Narwaria, A. Khosa, R.L. Dhar, S.K. |
author_sort | Narwaria, A. |
collection | PubMed |
description | The effect of alcoholic extract of the aerial parts of Artemisia vulgaris Linn on estrous cycle and implantation, in female albino rats, was studied. The drug induced an irregular estrous cycle with random disappearance of estrous phase and increase in the number of metestrus phases within the estrous cycle, observed for the total test period of 18 days. It exhibited 80% anti-implantation activity without showing any gross malformations in pups delivered, possibly due to its non-toxic nature even at the high dose of 3000 mg/kg p.o. These facts suggest the drug to possess some antifertility effect. |
format | Online Article Text |
id | pubmed-3336493 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1994 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33364932012-04-27 EXPERIMENTAL STUDIES ON ARTEMISIA VULGARIS – A POSSIBLE ANTIFERTILITY DRUG Narwaria, A. Khosa, R.L. Dhar, S.K. Anc Sci Life Original Article The effect of alcoholic extract of the aerial parts of Artemisia vulgaris Linn on estrous cycle and implantation, in female albino rats, was studied. The drug induced an irregular estrous cycle with random disappearance of estrous phase and increase in the number of metestrus phases within the estrous cycle, observed for the total test period of 18 days. It exhibited 80% anti-implantation activity without showing any gross malformations in pups delivered, possibly due to its non-toxic nature even at the high dose of 3000 mg/kg p.o. These facts suggest the drug to possess some antifertility effect. Medknow Publications & Media Pvt Ltd 1994 /pmc/articles/PMC3336493/ /pubmed/22556669 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Narwaria, A. Khosa, R.L. Dhar, S.K. EXPERIMENTAL STUDIES ON ARTEMISIA VULGARIS – A POSSIBLE ANTIFERTILITY DRUG |
title | EXPERIMENTAL STUDIES ON ARTEMISIA VULGARIS – A POSSIBLE ANTIFERTILITY DRUG |
title_full | EXPERIMENTAL STUDIES ON ARTEMISIA VULGARIS – A POSSIBLE ANTIFERTILITY DRUG |
title_fullStr | EXPERIMENTAL STUDIES ON ARTEMISIA VULGARIS – A POSSIBLE ANTIFERTILITY DRUG |
title_full_unstemmed | EXPERIMENTAL STUDIES ON ARTEMISIA VULGARIS – A POSSIBLE ANTIFERTILITY DRUG |
title_short | EXPERIMENTAL STUDIES ON ARTEMISIA VULGARIS – A POSSIBLE ANTIFERTILITY DRUG |
title_sort | experimental studies on artemisia vulgaris – a possible antifertility drug |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336493/ https://www.ncbi.nlm.nih.gov/pubmed/22556669 |
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