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ANTIMICROBIAL ACTIVITY OF CHEMOCONSTITUENTS OF ROOTS OF SALACIA MACROSPERMA

The ethanolic extract of roots of Salacia macrosperma (Hippocrataceae) exhibited significant in vitro antimicrobial activity. The ethanolic extract was fractionated with different solvents and all the fractions were screened for their antimicrobial spectrum against eight gram-positive, five gram-neg...

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Detalles Bibliográficos
Autores principales: Venkatesarulu, V., Kokate, C.K., Rambhau, D., Veeresham, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1992
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336611/
https://www.ncbi.nlm.nih.gov/pubmed/22556596
Descripción
Sumario:The ethanolic extract of roots of Salacia macrosperma (Hippocrataceae) exhibited significant in vitro antimicrobial activity. The ethanolic extract was fractionated with different solvents and all the fractions were screened for their antimicrobial spectrum against eight gram-positive, five gram-negative and ten fungal strains. Chloroform fraction followed by benzene fraction of enthanolic extract showed significant antimicrobial effect against all the microorganisms tested. The dose-dependent activity of fractions was evaluated against selected microbial strains and compared with appropriate standards.