Cargando…

EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES

Gymnema sylvestre, R. Br., popularly known as Meshashringi in Sanskrit and Sarkaraikolli in Tamil, was investigated for the control of type I (insulin dependent) diabetes in experimental animals. The hypoglycaemic extract was found to bring about blood glucose homeostasis, by increasing serum insuli...

Descripción completa

Detalles Bibliográficos
Autores principales: Shanmugasundaram, E. R. B., Venkatasubrahmanyam, M., Vijendran, N., Shanmugasundaram, K. Radha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336647/
https://www.ncbi.nlm.nih.gov/pubmed/22557613
_version_ 1782230980208099328
author Shanmugasundaram, E. R. B.
Venkatasubrahmanyam, M.
Vijendran, N.
Shanmugasundaram, K. Radha
author_facet Shanmugasundaram, E. R. B.
Venkatasubrahmanyam, M.
Vijendran, N.
Shanmugasundaram, K. Radha
author_sort Shanmugasundaram, E. R. B.
collection PubMed
description Gymnema sylvestre, R. Br., popularly known as Meshashringi in Sanskrit and Sarkaraikolli in Tamil, was investigated for the control of type I (insulin dependent) diabetes in experimental animals. The hypoglycaemic extract was found to bring about blood glucose homeostasis, by increasing serum insulin levels. The islets of langerhans appear to be restored or regulated by the herbal extract. Increased glycoprotein, which is the major metabolic abnormality in diabetes mellitus and the resultant nephropathy, retinopathy and micro and macroangiopathy, is brought under control by the administration of the leaf extract.
format Online
Article
Text
id pubmed-3336647
institution National Center for Biotechnology Information
language English
publishDate 1988
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-33366472012-04-27 EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES Shanmugasundaram, E. R. B. Venkatasubrahmanyam, M. Vijendran, N. Shanmugasundaram, K. Radha Anc Sci Life Original Article Gymnema sylvestre, R. Br., popularly known as Meshashringi in Sanskrit and Sarkaraikolli in Tamil, was investigated for the control of type I (insulin dependent) diabetes in experimental animals. The hypoglycaemic extract was found to bring about blood glucose homeostasis, by increasing serum insulin levels. The islets of langerhans appear to be restored or regulated by the herbal extract. Increased glycoprotein, which is the major metabolic abnormality in diabetes mellitus and the resultant nephropathy, retinopathy and micro and macroangiopathy, is brought under control by the administration of the leaf extract. Medknow Publications & Media Pvt Ltd 1988 /pmc/articles/PMC3336647/ /pubmed/22557613 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Shanmugasundaram, E. R. B.
Venkatasubrahmanyam, M.
Vijendran, N.
Shanmugasundaram, K. Radha
EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES
title EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES
title_full EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES
title_fullStr EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES
title_full_unstemmed EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES
title_short EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES
title_sort effect of an isolate from gymnema sylvestre, r. br. in the control of diabetes mellitus and the associated pathological changes
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336647/
https://www.ncbi.nlm.nih.gov/pubmed/22557613
work_keys_str_mv AT shanmugasundaramerb effectofanisolatefromgymnemasylvestrerbrinthecontrolofdiabetesmellitusandtheassociatedpathologicalchanges
AT venkatasubrahmanyamm effectofanisolatefromgymnemasylvestrerbrinthecontrolofdiabetesmellitusandtheassociatedpathologicalchanges
AT vijendrann effectofanisolatefromgymnemasylvestrerbrinthecontrolofdiabetesmellitusandtheassociatedpathologicalchanges
AT shanmugasundaramkradha effectofanisolatefromgymnemasylvestrerbrinthecontrolofdiabetesmellitusandtheassociatedpathologicalchanges