Cargando…
EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES
Gymnema sylvestre, R. Br., popularly known as Meshashringi in Sanskrit and Sarkaraikolli in Tamil, was investigated for the control of type I (insulin dependent) diabetes in experimental animals. The hypoglycaemic extract was found to bring about blood glucose homeostasis, by increasing serum insuli...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
1988
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336647/ https://www.ncbi.nlm.nih.gov/pubmed/22557613 |
_version_ | 1782230980208099328 |
---|---|
author | Shanmugasundaram, E. R. B. Venkatasubrahmanyam, M. Vijendran, N. Shanmugasundaram, K. Radha |
author_facet | Shanmugasundaram, E. R. B. Venkatasubrahmanyam, M. Vijendran, N. Shanmugasundaram, K. Radha |
author_sort | Shanmugasundaram, E. R. B. |
collection | PubMed |
description | Gymnema sylvestre, R. Br., popularly known as Meshashringi in Sanskrit and Sarkaraikolli in Tamil, was investigated for the control of type I (insulin dependent) diabetes in experimental animals. The hypoglycaemic extract was found to bring about blood glucose homeostasis, by increasing serum insulin levels. The islets of langerhans appear to be restored or regulated by the herbal extract. Increased glycoprotein, which is the major metabolic abnormality in diabetes mellitus and the resultant nephropathy, retinopathy and micro and macroangiopathy, is brought under control by the administration of the leaf extract. |
format | Online Article Text |
id | pubmed-3336647 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1988 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-33366472012-04-27 EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES Shanmugasundaram, E. R. B. Venkatasubrahmanyam, M. Vijendran, N. Shanmugasundaram, K. Radha Anc Sci Life Original Article Gymnema sylvestre, R. Br., popularly known as Meshashringi in Sanskrit and Sarkaraikolli in Tamil, was investigated for the control of type I (insulin dependent) diabetes in experimental animals. The hypoglycaemic extract was found to bring about blood glucose homeostasis, by increasing serum insulin levels. The islets of langerhans appear to be restored or regulated by the herbal extract. Increased glycoprotein, which is the major metabolic abnormality in diabetes mellitus and the resultant nephropathy, retinopathy and micro and macroangiopathy, is brought under control by the administration of the leaf extract. Medknow Publications & Media Pvt Ltd 1988 /pmc/articles/PMC3336647/ /pubmed/22557613 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Shanmugasundaram, E. R. B. Venkatasubrahmanyam, M. Vijendran, N. Shanmugasundaram, K. Radha EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES |
title | EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES |
title_full | EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES |
title_fullStr | EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES |
title_full_unstemmed | EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES |
title_short | EFFECT OF AN ISOLATE FROM GYMNEMA SYLVESTRE, R. BR. IN THE CONTROL OF DIABETES MELLITUS AND THE ASSOCIATED PATHOLOGICAL CHANGES |
title_sort | effect of an isolate from gymnema sylvestre, r. br. in the control of diabetes mellitus and the associated pathological changes |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3336647/ https://www.ncbi.nlm.nih.gov/pubmed/22557613 |
work_keys_str_mv | AT shanmugasundaramerb effectofanisolatefromgymnemasylvestrerbrinthecontrolofdiabetesmellitusandtheassociatedpathologicalchanges AT venkatasubrahmanyamm effectofanisolatefromgymnemasylvestrerbrinthecontrolofdiabetesmellitusandtheassociatedpathologicalchanges AT vijendrann effectofanisolatefromgymnemasylvestrerbrinthecontrolofdiabetesmellitusandtheassociatedpathologicalchanges AT shanmugasundaramkradha effectofanisolatefromgymnemasylvestrerbrinthecontrolofdiabetesmellitusandtheassociatedpathologicalchanges |