Expression of DNA transposable elements during nervous system development: A discussion about its possible functions

Transposable elements (retrotransposons and DNA transposons) comprise a large proportion of animal genomes, for example 20% in D. melanogaster, 36% in X. tropicalis and 45% in humans. After invading a new genome, the transposable element increases its copy number and subsequently accumulates mutatio...

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Detalles Bibliográficos
Autores principales: Faunes, Fernando, Lee-Liu, Dasfne, Larrain, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2011
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337140/
https://www.ncbi.nlm.nih.gov/pubmed/22545242
http://dx.doi.org/10.4161/mge.18550
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author Faunes, Fernando
Lee-Liu, Dasfne
Larrain, Juan
author_facet Faunes, Fernando
Lee-Liu, Dasfne
Larrain, Juan
author_sort Faunes, Fernando
collection PubMed
description Transposable elements (retrotransposons and DNA transposons) comprise a large proportion of animal genomes, for example 20% in D. melanogaster, 36% in X. tropicalis and 45% in humans. After invading a new genome, the transposable element increases its copy number and subsequently accumulates mutations. These may eventually result in inactive copies. Until recent days transposons have been considered “junk” DNA and no clear function have been assigned for this important amount of information on genomes.
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spelling pubmed-33371402012-05-07 Expression of DNA transposable elements during nervous system development: A discussion about its possible functions Faunes, Fernando Lee-Liu, Dasfne Larrain, Juan Mob Genet Elements Commentary Transposable elements (retrotransposons and DNA transposons) comprise a large proportion of animal genomes, for example 20% in D. melanogaster, 36% in X. tropicalis and 45% in humans. After invading a new genome, the transposable element increases its copy number and subsequently accumulates mutations. These may eventually result in inactive copies. Until recent days transposons have been considered “junk” DNA and no clear function have been assigned for this important amount of information on genomes. Landes Bioscience 2011-11-01 /pmc/articles/PMC3337140/ /pubmed/22545242 http://dx.doi.org/10.4161/mge.18550 Text en Copyright © 2011 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Commentary
Faunes, Fernando
Lee-Liu, Dasfne
Larrain, Juan
Expression of DNA transposable elements during nervous system development: A discussion about its possible functions
title Expression of DNA transposable elements during nervous system development: A discussion about its possible functions
title_full Expression of DNA transposable elements during nervous system development: A discussion about its possible functions
title_fullStr Expression of DNA transposable elements during nervous system development: A discussion about its possible functions
title_full_unstemmed Expression of DNA transposable elements during nervous system development: A discussion about its possible functions
title_short Expression of DNA transposable elements during nervous system development: A discussion about its possible functions
title_sort expression of dna transposable elements during nervous system development: a discussion about its possible functions
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337140/
https://www.ncbi.nlm.nih.gov/pubmed/22545242
http://dx.doi.org/10.4161/mge.18550
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