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Optimization and stabilization of Rho small GTPase proteins for solution NMR studies: The case of Rnd1

Rho GTPases of the Ras superfamily have important roles in regulating the organization of the actin filament system, morphogenesis and migration of cells. Structural details for these proteins are still emerging, and information on their dynamics in solution is much needed to understand the mechanis...

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Detalles Bibliográficos
Autores principales: Cao, Shufen, Buck, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337157/
https://www.ncbi.nlm.nih.gov/pubmed/22545226
http://dx.doi.org/10.4161/sgtp.19257