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Dose dense 1 week on/1 week off temozolomide in recurrent glioma: a retrospective study

Alternative temozolomide regimens have been proposed to overcome O(6)-methylguanine-DNA methyltransferase mediated resistance. We investigated the efficacy and tolerability of 1 week on/1 week off temozolomide (ddTMZ) regimen in a cohort of patients treated with ddTMZ between 2005 and 2011 for the p...

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Detalles Bibliográficos
Autores principales: Taal, Walter, Segers-van Rijn, Joyce M. W., Kros, Johan M., van Heuvel, Irene, van der Rijt, Carin C. D., Bromberg, Jacoline E., Sillevis Smitt, Peter A. E., van den Bent, Martin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337418/
https://www.ncbi.nlm.nih.gov/pubmed/22396071
http://dx.doi.org/10.1007/s11060-012-0832-5