Effects of sequence variation on differential allelic transcription factor occupancy and gene expression

A complex interplay between transcription factors (TFs) and the genome regulates transcription. However, connecting variation in genome sequence with variation in TF binding and gene expression is challenging due to environmental differences between individuals and cell types. To address this proble...

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Detalles Bibliográficos
Autores principales: Reddy, Timothy E., Gertz, Jason, Pauli, Florencia, Kucera, Katerina S., Varley, Katherine E., Newberry, Kimberly M., Marinov, Georgi K., Mortazavi, Ali, Williams, Brian A., Song, Lingyun, Crawford, Gregory E., Wold, Barbara, Willard, Huntington F., Myers, Richard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337432/
https://www.ncbi.nlm.nih.gov/pubmed/22300769
http://dx.doi.org/10.1101/gr.131201.111

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