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Fatal Pneumonitis Induced by Oxaliplatin: Description of Three Cases

We describe 3 fatal cases of interstitial pneumonitis rapidly evolving to pulmonary fibrosis and death after the administration of oxaliplatin as part of the FOLFOX regimen. Due to the widespread use of oxaliplatin in oncology, clinicians should be aware of the risk and severity of oxalipatin-induce...

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Detalles Bibliográficos
Autores principales: Pontes, L.B., Armentano, D.P.D., Soares, A., Gansl, R.C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3337737/
https://www.ncbi.nlm.nih.gov/pubmed/22539922
http://dx.doi.org/10.1159/000337030
Descripción
Sumario:We describe 3 fatal cases of interstitial pneumonitis rapidly evolving to pulmonary fibrosis and death after the administration of oxaliplatin as part of the FOLFOX regimen. Due to the widespread use of oxaliplatin in oncology, clinicians should be aware of the risk and severity of oxalipatin-induced interstitial pneumonia.